Bio Assay & Screening

Bioassay and Screening: Scope, Samples and Results

Tamilnadu Test House provides testing services for a wide range of enzyme assays, immuno assays, cell-free assays and cell based assays for the biologics & biosimilar development across all stages of discovery and development, starting with R & D, Preclinical and Clinical phases to lot release, in-process validation and stability testing. We provide essential testing that establishes the safety and potency of biopharmaceuticals as well as determines pharmacokinetic and pharmacodynamic profiles.

What is a bioassay?

A bioassay evaluates a biological response under defined experimental conditions. Depending on its purpose, it can support investigations of activity, potency or another specified biological characteristic.

Our assays use methodologies including ELISA & CLIA, and different end point readout to identify specific activity & potency of the molecules. For these, specific studies we will be using Multimode plate readers (absorbance, fluorescence, time resolved fluorescence, luminescence), FACS and microscopes.

Selection depends on the product, biological mechanism, development stage and decision the result must support. Define the assay objective, sample characteristics, reference material and acceptance approach with the laboratory.

Assay development, validation and technology transfer:

We provide clients with method development, method validation and method transfer. Bio-assays and Analytical methods can be developed at Tamilnadu Test House and is transferred according to client requirement to be used in the client place. For background on controlled comparison materials in quality testing, read about reference and working standards.

Tamilnadu Test House offers the following bioassay services: